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Bisphenol A (BPA) is a chemical first synthesized more than 100 years ago; it is frequently used for the production of polycarbonate plastics and epoxy resins. []. Numerous recent. El BPA se utiliza, por ejemplo, en plásticos de policarbonato, un tipo de plástico transparente y rígido utilizado para fabricar dispensadores de agua, recipientes de almacenamiento y botellas de bebidas. Bisphenol-A (BPA) is an industrial chemical used in plastics and added to many products, such as food containers, baby bottles, and plastic water bottles. , lacquer coatings), and dental composites/sealants. Introduction. In the body, these chemicals can act like hormones or. The project began in 2012 as a unique collaboration among NIEHS, the National Toxicology Program, and the U. e. 29. e. Bisphenol A. LinkedIn. , 2012; Huang et al. 2-4 Studies suggest numerous health disorders. Dioxins are a byproduct of certain manufacturing processes, such as herbicide production and paper bleaching. D. The demand for BPA is driven by demand for polycarbonate (PC) products, and demand from the epoxy resins sector is lower, consuming roughlyBisphenol A (BPA) is the most used colour developer in thermal paper for cashiers receipts, labels, and tickets. BPA can migrate into food from the material or. 1INFO NASIONAL – Guru Besar Fakultas Kesehatan Masyarakat, Universitas Hasanuddin (Unhas), Prof. BPA significa bisfenol A, una sustancia química industrial que se ha utilizado para fabricar ciertos plásticos y resinas desde los años cincuenta. For chronic renal patients, there was a positive association between plasma BPA and disease severity. Bisphenols are a group of compounds containing two phenyl rings connected to each other with a small linking group (Fig. In the mid-1930s, scientists determined it was a synthetic estrogen. Several reports suggest that BPA may have estrogen receptor-independent effects. ビスフェノール A (bisphenol A, BPA) は化学式 (CH 3) 2 C (C 6 H 4 OH) 2 の 有機化合物 である。. It is an endocrine disruptor that has been linked to many negative health effects, including cardiovascular. 它是一种 有机化合物 ,具有两个 酚 官能团 。. 双酚A被用于合成 聚碳酸酯 塑料和 环氧树脂 等。. In zebrafish, 50 μM BPA exposure induces otic vesicle abnormalities, including otolith aggregation. 2 percent of total European BPA consumption (JRC-IHCP 2010). contact with thermal paper, some residual BPA is found at trace levels in the final product of resin-based dental materials. Obtenue par réaction entre deux équivalents de phénol et un équivalent d' acétone, sa molécule comporte deux groupements fonctionnels phénol. Bisphenol A (BPA) is widely used in many consumer products, epoxy resins, and polycarbonate plastics such as baby bottles and the lining of beverage cans. Patrick Allard, in Biomarkers in Toxicology, 2014. 一种 化工原料 ,是已知的 内分泌干扰素 ( 环境荷尔蒙 )。. An overcoated SPME fiber provides the durability necessary for direct immersion into foods such as canned soup and pumpkin, allowing for low level. Untuk lebih jelasnya apa itu BPA, simak yuk Moms penjelasan di bawah ini. BPA berpotensi membahayakan otak, menyebabkan gangguan perilaku, serta mengganggu sistem hormon yang berakibat buruk pada. Piotr Czub, Piotr Czub. BPA is produced on an industrial scale by the condensation reaction of phenol and acetone. €4327 EUR $4,600 USD £3,745 GBP. This coating keeps the food from contacting the metal and helps increase the shelf-life of. Potential similarities in toxicological profiles have raised. It is a hazard in the prenatal period because of its presence in the placenta, fetal membranes, amniotic fluid , maternal and fetal blood and its ability to cross the placenta. BPA mimics the actions of estrogen on multiple levels by activating estrogen receptors α and β. BPA is a chemical used to make rigid plastics, including food storage containers and refillable drinks bottles. 201-245-8. It can imitate the body's natural hormones and interfere with their function. , and is incorporated into soil/water through leaching. HCl) to be used as a catalyst. Bisfenolo A. , in food containers, water bottles, thermal papers, toys, medical devices, etc. Bisphenol A (BPA), a toxic endocrine disruptor, is widely distributed in the environment, and the effects of BPA exposure on human health outcomes are a critical issue. Bisphenol A (BPA) is widely used in many consumer products, epoxy resins, and polycarbonate plastics such as baby bottles and the lining of beverage cans. Bisphenols (BPA: 2,2-bis(4-hydroxyphenyl) propane or 4,4′-(propane-2,2-diyl)diphenol) are a group of chemical compounds (bisphenol B (BPB), bisphenol F (BPF) and bisphenol S) that consist of two phenolic rings joined together through abridging carbon or other chemical structure. Everyone is exposed to BPA through skin, inhalation,. Somit können Produkte aus diesen Materialien noch freie Bisphenol A-Reste enthalten. 1). 1. Figure 1 1: Bisphenol A. Il bisfenolo A, solitamente abbreviato in BPA, è un composto organico di sintesi con due gruppi fenolici geminali. In 2012, the organization banned BPA from. BPA was originally listed as causing reproductive toxicity on April 11, 2013 for the developmental toxicity endpoint, but subsequently delisted pending resolution of a court case. 雙酚A在食品容器具中的用途是什麼?Bisphenol-A (BPA) is a synthetic chemical ubiquitous in the environment and listed as an endocrine disruptor. bisphenol A (BPA), a colourless crystalline solid belonging to the family of organic compounds; its molecular formula is C 15 H 16 O 2. 一种 化工原料 ,是已知的 内分泌干扰素 ( 环境荷尔蒙 )。. Những phụ nữ béo phì thường có nồng độ BPA cao hơn 47% so với những phụ nữ có cân nặng bình thường. It is a most common plasticizer that is used widely to produce epoxy resin and polycarbonate plastics, enters the living system through food and water contamination and generates health hazards. In 2008, the possible health risks of Bisphenol A (BPA) -- a common chemical in plastic -- made headlines. This type of plastic is used to make some types of beverage containers, compact disks, plastic dinnerware, impact-resistant safety equipment, automobile parts, and toys. Industrially an excess of phenol is used to ensure. BPA (bisphenol-A) adalah bahan kimia yang ditambahkan ke banyak produk komersial, termasuk wadah makanan dan produk kebersihan. Consider using fresh and frozen foods instead of canned foods. In August 2008. Bisphenol A: belastete Konserven. 它是一种 有机化合物 ,具有两个 酚 官能团 。. Click to read some of the common myths about BPA and the realities we know from extensive scientific study. BPA was first synthesized by Dianin as early as 1891. It was one of the first compounds to be identified as an endocrine disruptor that was capable of disrupting the endocrine system. 20世纪30年代中期人们就发现了双酚A可以发挥 雌. What is bisphenol A (BPA)? BPA (CASRN 80-05-7) is a synthetic chemical used as a monomer to produce certain polycarbonate plastics and epoxy resins. As a major bisphenol, BPA has a high production volume (Vandenberg et al. Human epidemiological studies have reported adverse behavioral outcomes with BPA exposure in children, however, corresponding effects on children’s brain structure have. The conjugation step. EINECS: No. BPA – 2. In the body, these chemicals can act like hormones or. Jakarta – Bisphenol A, atau yang lebih dikenal sebagai BPA, adalah senyawa kimia yang telah menjadi perhatian selama beberapa tahun terakhir karena potensi dampak negatifnya terhadap. ,. BPA was re-listed as causing reproductive toxicity on May 11, 2015 for the female reproductive toxicity endpoint. Bisphenol A (BPA) is a chemical that is used to manufacture polycarbonate plastic, which may be used to make certain food contact materials such as water dispensers or articles for food production. BPA is an endocrine disruptor, which can mimic human hormones and maybe lead to negative health effects [1,2]. SUMMARY: Bisphenol A (BPA) is a plastic found in some hard plastic (polycarbonate) water bottles, baby bottles, infant cups, and metal can linings, including the linings of some canned baby formula. 2015). Penelitian tersebut. Prenatal or in utero exposure to BPA. Por su capacidad de unirse a los receptores de estrógenos(hormona segregada por el ovario y que induce la aparición de los caracteres sexuales femeninos,. Price. Jedná se o derivát difenylmethanu. BPA can contaminate food, beverage, air, and soil. Goodman, M. Due to its relatively well-known harmful effects on living organisms, BPA is often replaced by its various. These include growth, cell repair, fetal development,. Introduction. 1. What is BPA, and where is it found? The plastics chemical bisphenol A was first synthesized in 1891. 双酚a,也称bpa,是一种有机化合物,分子式为c15h16o2,在工业上双酚a被用来合成聚碳酸酯(pc)和环氧树脂等材料。60年代以来就被用于制造塑料(奶)瓶、幼儿用的吸口杯、食品和饮料(奶粉)罐内侧涂层。bpa无处不在,从矿泉水瓶、医疗器械到及食品包装的内里,都有它的身影。Â The packaging sector is an important industry. BPA is a chemical used to make rigid plastics, including food storage containers and refillable drinks bottles. Until recently, BPA was also widely used to make the protective coatings inside food and drink cans, but US manufacturers have been phasing it out in response to consumer demand and scientific findings of serious health concerns. Bisphenol A (BPA) (2,2-bis(4-hydroxyphenyl)propane; BPA) is an organic synthetic compound, belonging to the group of diphenylmethane derivatives and bisphenols. BPA has recently been classified as a substance of great concern by the European Union (EU). Bisphenol A (BPA, 80-05-7) is an organic compound used predominantly in the production of products made of polycarbonate plastic and epoxy resins that line food and beverage cans. It is also widely known for. Introduction Bisphenol A (BPA), an endocrine-disrupting compound, is a common organic pollutant found in a variety of wastewaters around the world. A significant volume of BPA produced worldwide is. Peterson, in Encyclopedia of Toxicology (Third Edition), 2014 Abstract. Health. BPA is a synthetic phenol extensively used in the manufacture of polycarbonate plastics and epoxy resins. J. BPA is suspected to be associated with several chronic human health. It has the tendency of migrating into food stored in materials containing it. There is incomplete understanding of BPA toxicokinetics, and there are no established interventions to eliminate this compound from the human body. Kata kunci: plastik, GC/MS, fragmentasi, indeks retensi, BPA, DEHP Abstract There are many polycarbonate plastics are used in the community, and these plastics contain compounds such as bisphenol A (BPA). È una molecola usata come additivo nella produzione di diversi materiali, in particolar modo plastiche, ma anche resine epossidiche utilizzate per il rivestimento. , 2002). Bisphenol-A (BPA) has been reported to be associated to female infertility. The Total Addressable Market (TAM) for Bisphenol-A (BPA) had a share of 7,082 metric tons in 2022. Sources of exposure to BPA include: Some linings in metal food and drink cans, jar lids, and bottle caps. The decreasing trend was statistically significant. It is expected to reach 12,169 metric tons by 2031, growing at a CAGR of 6. Since the 1960s, a wide range of products have contained BPA. Due to its mass productions and widespread applications, the presence of BPA is ubiquitous in the environment. Bisphenol A (BPA) is a widely used chemical that has been shown to adversely affect health outcomes in experimental animal studies, particularly following fetal or early life exposure. New research on very-low-dose exposure to BPA suggests an association with adverse health effects, including breast and prostate cancer. Annual production of BPA in 2015 was estimated at about 4. ANSES has identified nearly 60 industry sectors in France potentially using this substance. BPA is a synthetic phenol extensively used in the manufacture of polycarbonate plastics and epoxy resins. 2 Polikarbonat banyak digunakan sebagai bahan kemasan. Food and Drug Administration (FDA), and it included key contributions from. Bisphenol A (BPA) is a high production endocrine disrupting chemical found in numerous consumer products. Bisphenol A (BPA) is an organic synthetic compound serving as a monomer to produce polycarbonate plastic, widely used in the packaging for food and drinks, medical devices, thermal paper, and dental materials. Bisphenol A (BPA) is a chemical produced in large quantities for use primarily in the production of polycarbonate plastics used in various products including shatterproof windows, eyewear, water bottles, and epoxy resins which coat some metal food cans, bottle tops, and water supply pipes. It is possible to observe that only four papers showed data about free BPA levels (Calafat et al. BPA, bisphenol F (BPF), bisphenol S (BPS), and bisphenol AF (BPAF) were found in 12 kinds of food samples except for bisphenol B (BPB). It was first reported by a Russian chemist. 1. It has two unsaturated phenolic rings attached by a bridging carbon. Jedná se o derivát difenylmethanu. The diagrammatic representation of the bisphenol A structure is. BPA (Bisphenol A) is a chemical used in certain food contact materials and first approved by FDA in the early 1960s. , 2015). "Bisphenol" is a common name; the letter following denotes the variant, which depends on the additional. BPA stands for bisphenol A, an industrial chemical that has been used to make certain plastics and resins since the 1950s. 29 g/mol and chemical structure of C 15 H 16 O 2 (Fig. Until recently, there were relatively few epidemiological studies examining the relationship between BPA and health effects in humans. Four scientific articles analyze and discuss exposure to bisphenol A (BPA, CAS 80-05-7) and its analogues as well as potential associated health risks, e. The main reason for using BPA is that it enhances crucial properties such as durability and heat resistance for a wide range of plastic products. Bisphenol A (BPA) is a compound used in the manufacture of a wide variety of everyday materials that, when released into the environment, causes multiple detrimental effects on humans and other organisms. Bisphenol A (BPA) is a synthetic chemical compound that is used to make a variety of products, including plastics and resins. com, BPA dikembangkan sejak 1930-an. BPA pertama kali ditemukan pada tahun 1890-an, tetapi ahli kimia pada 1950-an menyadari bahwa ini dapat dicampur dengan senyawa lain untuk menghasilkan plastik polikarbonat yang kuat dan tangguh. The current study thus addresses the need for a simple and user-friendly analytical. Bisphenol A (BPA), one of the most widely consumed endocrine disrupting chemicals, has been found to be associated with a variety of diseases, especially cardiovascular diseases. BPA readily leaches out from these products into the environment and into foodstuffs (from packaging materials) and human exposure can be considerable. Dietary exposure to bisphenol A (BPA) is a health concern for consumers across all age groups, EFSA’s scientific experts have concluded in a new re-evaluation. The aim of the study was to determine totoxicity of bisphenol A (BPA) and its derivatives (bisphenol S (BPS), bisphenol F (BPF), and tetrabromobisphenol A (TBBPA)) due to its high accumulation in environment. What is Bisphenol A? BPA is a high production volume (HPV) chemical widely used in manufacturing polycarbonate plastics and epoxy resins used in nearly. Bisphenol A; BPA. , Some BPA alternatives, such as bisphenol S (BPS), have. Bisphenol A Metabolites Glucuronidated form of bisphenol A. This is a single user license, allowing one user access to the product. Peneltian. Dibandingkan dengan orang dewasa, anak-anak cenderung lebih rentan terhadap paparan bahan kimia. In addition, in procedures of medically assisted reproduction BPA exposure has been found to be negatively associated with peak serum. A deterministic approach was used to calculate the dietary intakes of 4 kinds of compounds. Bisphenol A (BPA) is a chemical substance used in combination with other chemicals to manufacture certain plastics and resins. In North America, over 90% of the population has detectable levels of urinary BPA. BPA is a chemical component present in polycarbonate plastic used in the manufacture of certain beverage containers and many food and beverage can liners. Untuk lebih jelasnya apa itu BPA, simak yuk Moms penjelasan di bawah ini. 1. Đây là một chất rắn không màu, hòa tan trong dung môi hữu cơ, nhưng tan kém. The chemical structure and the physicochemical properties of BPA are shown in Table 2. BPA is also used in the manufacture of epoxy resins which act as a protective lining on the inside of some metal-based food and beverage cans. Among them, the most widely used in industry is bisphenol A (BPA), which was discovered in 1891 []. Several reports suggest that BPA may have estrogen receptor-independent effects. Subsequently, BPA has been used in many consumer products, including plastics (as a polymer, i. People are generally exposed to minute levels of BPA, mostly from the. 29 g/cm 3. Bisphenols. 雙酚A(Bisphenol A,縮寫為BPA),又稱酚甲烷。一種化工原料,是已知的內分泌干擾素(環境荷爾蒙)。 它是一種有機化合物,具有兩個酚 官能團。 雙酚A被用於合成聚碳酸酯塑料和環氧樹脂等。. Bisphenol A (BPA) is a chemical additive used in the manufacturing of many plastics and resins and found in a plethora of consumer products. Les substances chimiques telles que le BPA utilisées dans les contenants alimentaires. BPA epoxy resins are used in the protective linings of food cans, in dental sealants, and in other products.